IL1B and cutaneous melanoma: A relationship between MITF and inflammation is known to exist in cutaneous melanoma: Arts et al. showed that IL1β decreased MITF-M expression, partly through an upregulation of miR-155 in human cutaneous melanoma cell lines, and that samples with high MITF and TYR (tyrosinase) expressed low IL1β in a mouse model and vice versa [47].