Ghrelin has also been found to attenuate intestinal ischemia-induced injury in mice by activating the mammalian target of rapamycin (mTOR) signaling [115], as well as decrease sepsis-induced lung injury by blocking AKT, inducible nitric oxide synthase (iNOS), and nuclear factor kappa B (NF-kB) signaling in alveolar macrophages [116]. The gene discussed is MTOR; the disease is Sepsis.