TP53 and prostate cancer: In order to assess the downstream targets of wt-ANXA7, DN-ANXA7J, or p53 in prostate cancer cells, we isolated mRNAs from the normal prostate epithelial cell line PREC and from the prostate cancer cell DU145, which had been transfected with either the vector alone, wt-ANXA7, DN-ANXA7J, or p53.