TNFRSF8 and anaplastic large cell lymphoma: Takeshita M et al. reported that strongly CD30-expressing ATL was grouped into three types: diffuse CD30+ anaplastic large cell lymphoma (group 1); pleomorphic-type lymphoma with diffuse CD30 expression (group 2); and pleomorphic-type lymphoma with positive CD30 expression in large cells, but negative in medium-sized and small cells (group 3) [49].