B-cell NHLs frequently express CD27/CD27L (TNFRSF7/TNFSF7), CD30 or CD30L (TNFRSF8 or TNFSF8), CD40 (TNFRSF5), and TNFRs/TNF positive (TNFRSF1 and 2/TNFSF2), but T-cell NHLs show expression of CD30, CD40L (TNFSF5), and TNFRs/TNF [4]. The gene discussed is TNFSF8; the disease is B-cell non-Hodgkin lymphoma.