Patients carrying the T allele of the HLA-C rs12191877 SNP or the C allele of the TNF-1031 (rs1799964) SNP are associated with greater pharmacological survival of anti-TNF drugs, while patients who have not developed psoriatic arthritis or are carriers of the G allele of the TLR5 rs5744174 polymorphism, the A allele of CD84 rs6427528 or the T allele of PDE3A rs11045392, which is in linkage disequilibrium with SLCO1C1 rs3794271, are associated with longer UTK survival. The gene discussed is TLR5; the disease is psoriatic arthritis.