In particular, the HLA-C rs12191877 polymorphism was associated with the response to anti-TNF drugs (a reduction of 75% in psoriasis area and severity index score [PASI 75] at 3 months) in 144 white patients (from Spain) (OR = 0.30, 95% CI = 0.11–0.88, p = 0.027) [37]. Here, HLA-C is linked to psoriasis.