In particular, a meta-analysis of genome-wide association studies (GWAS) with white patients (13 studies/2706 patients) diagnosed with rheumatoid arthritis and treated with anti-TNF showed that the CD84 rs6427528-AG genotype was associated with greater effectiveness of treatment with ETN (733) (p = 0.004) [51]. The gene discussed is CD84; the disease is rheumatoid arthritis.