To investigate whether OsNPR1 could influence the expression of Xoo Hrp genes, we checked the expression profiles of all Xoo hrp genes in RNAseq data and found six Hrp genes (HrpA1/PXO_RS00410, HrpB/PXO_RS00390, HrpB2/PXO_RS00375, HrpB4/PXO_RS00385, HrpB8/PXO_RS00405, and HrpD6/PXO_RS00325) were downregulated in OsNPR1-OE plants after PXO99A infection, indicating that OsNPR1 might restrict the delivery of Xoo effectors into plant cells by repressing Hrp gene expression (Figure 6). This evidence concerns the gene POLR2H and infection.