MAPK8 and coronary artery disorder: This miR could potentially be involved by regulating inflammatory cytokines through the JNK signaling pathway [26] or the phosphatidylinositol 3-hydroxy kinase [PI3K]/protein kinase B [AKT] pathway [27], which would cause vascular smooth muscle cell proliferation and migration, resulting in more severe vascular stenosis and worsening CAD [28].