Conversely, its overexpression in pancreatic cancer cell lines led to inhibition of proliferation and migration, reduced colony formation efficiency compared to control cells, and decreased expression of β-catenin/TCF4 targets such as Jun proto-oncogene (JUN), MYC proto-oncogene (MYC), cyclin D1 (CCND1), and snail family transcriptional repressor 1 (SNAI1) [93]. This evidence concerns the gene SNAI1 and familial pancreatic carcinoma.