In the present study, we specify the candidate target genes for mir-483-5p in heart tissue, among them PLA2G5, GRK2, MYOM2, TIMP2, ADAMTS2 and HGSNAT. Indeed, regulation of many of these genes related to cardiovascular diseases and correlated with MI in previously published reports [26,27,28,29,30,31] (Scheme 2). Here, GRK2 is linked to cardiovascular disorder.