The Kelch-like ECH-associated protein 1 (Keap1)-Nrf2-antioxidant response element (ARE) pathway plays a principal role in the adjustment of oxidative stress and homeostasis of the reverse inflammatory reaction by regulating not only antioxidant genes, but also detoxification genes for operating and degrading cancer-causing agents and toxic elements [4]. Here, KEAP1 is linked to cancer.