The antitumoral role of miRNA-101-3p has also been reported in HNSCC where, according to Panvongsa et al. [39], BM-MSCs-derived EVs overexpressing miR-101-3p were able to suppress cancer cell proliferation and tumor growth both in vitro and in vivo by targeting the Collagen Type X Alpha 1 Chain gene (COL10A1), resulting in downregulation of Collagen X expression. Here, COL10A1 is linked to head and neck squamous cell carcinoma.