Interestingly, we found that carriers of the CDKN2Ars2811710C allele, which is associated with an increased risk of MM, had decreased numbers of CD4+EMCD45RO+ CD27− T memory cells, which are cells that display a high antigen recall response and were reported to be poorly represented in MM patients compared to controls [74]. The gene discussed is CD27; the disease is Miyoshi myopathy.