We also found that homozygous carriers of the CD46rs1142469A allele, which was associated with an increased risk of MM, had decreased numbers of CD19+ B cells, CD19+CD3− B cells, CD5+IgD− cells, IgM− cells, IgD−IgM− cells, and CD4−CD8− PBMCs compared with those subjects carrying the G allele (p = 0.00025–0.00086; Figure 2A–F). The gene discussed is CD19; the disease is Miyoshi myopathy.