TP53 and cancer: Upon KEGG (Figure 5H) and Reactome (Figure 5I) pathway interpretation further consistent oncology (“p53 signaling pathway”, “transcriptional misregulation in cancer”, “TP53 regulates cell cycle genes”), metabolism (“insulin resistance”, “AGE-RAGE signaling pathway in diabetic complications”), stress (“biological oxidations”) and cell fate/damage (“cellular senescence”, “intrinsic pathway for apoptosis”) multidimensional phenotype was evident.