INS and obesity due to melanocortin 4 receptor deficiency: Another 77 patients (32.35%), had BP values normale or slightly elevated (129–120/80–75 mmHg), and almost all of them (91.78%) had other associate clinical conditions like these: severe heart diseases (50.1%), diabetes (32.56%: 87.3% with oral antidiabetic treatment and 12.7% with insulin intake) and obesity (15.16%).