With a focus on the association between salivary testing antibodies and RA manifestations, one study reported an association between anti-PAD4 salivary antibodies and RA disease duration [27], while Ljungberg et al. identified ACPA salivary levels to be statistically associated with disease activity as determined by DAS28 in linear regression analysis (p=0.016) [28]. Here, PADI4 is linked to rheumatoid arthritis.