Across the collection and within the ALS group, LCL-derived iPSCs were generated from five patients with mutations in ANXA11 (2× G38R, 2× D40G, 1× R235Q), three with TARDBP mutations (1× M337V, 1× G348V, 1× N378D), four with C9ORF72 GGGGCC intronic expansions, three with mutations in FUS (1× R519E, 1× R521H, 1× R522G), and four with mutations of unknown significance in ARPP21 (3× P529L, 1× P713L). Here, ARPP21 is linked to amyotrophic lateral sclerosis.