COMT and major depressive disorder: The Genecept Assay results analysis covers a wide range of drugs used for the psychopharmacotherapy of mental disorders, including depression, obsessive-compulsive disorders, schizophrenia, attention deficit hyperactivity disorder, bipolar disorder, etc. The study is conducted on allelic variants in 20 genes, including 5HT2C, MC4R, DRD2, COMT, and the genes encoding key liver cytochrome P450 isoenzymes.