Keratopathy is also present in inborn errors of metabolism, including mucopolysaccharidoses, mucolipidoses, cystinosis, tyrosinemia type II, Wilson disease, Fabry disease, Lecithin Cholesterol Acyltransferase Deficiency (LCAT)-related metabolic disease, and Tangier disease [8]. This evidence concerns the gene LCAT and Tangier disease.