DNASE1L3 and systemic lupus erythematosus: Common variants in Deoxyribonuclease 1 Like 3 (DNASE1L3) have been associated with a slight elevation in the risk of SLE; the GWAS-linked SNP in DNASE1L3 associated with these diseases does not completely inhibit the function of DNase, but decreases its levels of secretion [59].