BAP1 and Leigh syndrome: Other syndromes with less frequency predispose to renal tumors, including the Tuberous Sclerosis Complex (TSC) with a 4% lifetime risk (lft), Li–Fraumeni syndrome (LF), Bloom syndrome (BSyn), Fanconi Anemia, BAP1 tumor predisposition syndrome (BAP1) with up to 10% lft, Lynch syndrome (LS) with up to 16% lft, MUTYH-associated polyposis (MAP), and hereditary diffuse gastric cancer syndrome (HDGC) with up to 10% lft.