In parallel, the spinal exposure to recombinant fractalkine reversed the glabridin-induced reductions of CX3CR1 (F(3, 16) = 21.36; p < 0.0001; n = 5; one-way ANOVA; Figure 5C) and Iba-1 (F(3, 16) = 51.46; p < 0.0001; n = 5; one-way ANOVA; Figure 5D) expressions in the dorsal horn of the rodents undergoing bone fractures. Here, AIF1 is linked to bone fracture.