MAPT and early-onset autosomal dominant Alzheimer disease: Bader et al. [123] identified over 1000 proteins that register differing levels between Alzheimer’s disease and non-Alzheimer’s disease cerebrospinal fluid, including well-known neurodegeneration-related proteins such as tau, superoxide dismutase 1 (SOD1), and Parkinson disease protein 7 (PARK7).