Since RAF/MEK/ERK pathway seems to be involved in viral survival, Ghasemnejad- Berenji et al. in 2021 suggested this pathway as a potential therapeutic strategy for COVID-19: in fact, authors highlighted that the RAF/MEK/ERK signalling cascade is probably one of the most well-known signal transduction pathways in biology, since it is involved in a wide variety of cellular functions, such as apoptosis, cell proliferation and cell cycle arrest [8]. The gene discussed is RAF1; the disease is COVID-19.