Barassi A et al. (2012) [139] and Korantzopoulos P et al. (2008) [140] confirmed that in patients with persistent AF and preserved LVEF, elevated hs-CRP levels independently predicted subacute AF recurrence rate, whereas NT-proBNP concentrations were not associated with arrhythmic outcome but corresponded to the alterations of cardiac hemodynamics secondary to the presence of AF. The gene discussed is CRP; the disease is atrial fibrillation.