Evidence suggested that some medications used to treat BD may be protective against accelerated ageing effects; in fact, a positive correlation between the most frequently used mood stabilise (lithium), and its duration treatment and telomere length has been demonstrated [40,41,42]; furthermore, older patients with BD seem to present higher levels of growth differentiation factor 15, a biomarker of ageing associated with a longer length of illness [42]. Here, GDF15 is linked to Behcet disease.