DDIT3 and Fanconi anemia: These genes include DDIT3 (DNA damage-inducible transcript 3) [34], FANCM (Fanconi anemia, complementation group M) [35], Merlin tumor suppressor [36,37], NME1 (NME/NM23 nucleoside diphosphate kinase 1) [38], SMAD4 [39,40].