PTEN and breast cancer: The other study conducted on 130 breast cancer patients tested by multigene panel analysis (BRCA1, BRCA2, TP53, STK11, CDH1, PTEN, PALB2, CHEK2, ATM), highlighted BRCA1 c.3607C>T as the most common variant in the group, prevalent in triple-negative invasive carcinomas [12].