Lower cervical sections selected from the ALS spinal cord and the corresponding control tissues were contrasted with Cresyl violet (Figure 4D(D1)) to identify and locate motor neurons in the grey matter of the ventral horn and guide the orientation and selection of subsequent tissue sections to be probed by specific antibodies against STING and toxic protein aggregates (TDP-43). The gene discussed is STING1; the disease is amyotrophic lateral sclerosis.