Previously, FSRH, INHA, ESR1, and BMP15 gene polymorphisms have been studied with regard to the conditions of the female reproductive system, including polycystic ovary syndrome, poor ovarian response, POI, breast cancer, and endometriosis, as well as male infertility [50,57,58,59,60,61,62,63,64,65,66,67]. This evidence concerns the gene ESR1 and male infertility.