LTA and medulloblastoma: Even more importantly, the metabolic and lipidomic profile of cerebrospinal fluid from patients with medulloblastoma, the most common malignant brain tumor in childhood, are distinctive in terms of their TNF-beta, TNF-alpha, and adipogenesis signatures, allowing the classification of patients with medulloblastoma by analyzing their cerebrospinal fluid and comparing it to that of normal patients [79].