Moreover, mutations in the fibroblast growth factor receptor (FGFR) family have been identified and characterized in different pediatric brain tumor types via large-scale genetic analysis, such as recurrent FGFR1 somatic mutations (N546K and K656E), FGFR1–TACC1 gene fusions, and duplications of the FGFR1 tyrosine kinase domain in patients with PA and dysembryoplastic neuroepithelial tumors (DNETs) [66]. This evidence concerns the gene FGFR1 and brain neoplasm.