Although genetic PD corresponds to a small fraction of all cases, focusing the research on genetic forms has proved to be valuable to understanding the pathophysiology of PD, since some of the proteins encoded by PD-associated genes are involved in key neuropathological mechanisms linked to the development and progression of both sporadic and familial PD [15]; these include α-synuclein aggregation and accumulation, mitochondrial dysfunction, proteasomal and autophagic impairment, oxidative stress, and neuroinflammation [2]. This evidence concerns the gene SNCA and Parkinson disease.