We found an upregulation of genes related to lipid control (e.g., OLAH, LPL, ECHDC3, ALOX15B, PCSK9), oxidation (e.g., MAOA, MAOB), polyubiquitination, and metalloproteinases in patients with ARDS by day 7 of hospitalization. This evidence concerns the gene OLAH and acute respiratory distress syndrome.