However, in recent years, HBB expression has been detected in non-erythroid tissues such as neuronal cells [13], retinal epithelial cells [9], endometrial cells [25], cervical epithelial cells [4], type II alveolar epithelial cells [6,8], mesangial cells [10], hepatocytes [11], and tumor tissues [4,15,16,26,27]. The gene discussed is HBB; the disease is neoplasm.