TF and systemic sclerosis: Upon PHA stimulation, increased percentages of CD25+ and HLA-DR+ cells were found in T1-like and T1/17-like (CXCR5− non-Treg) CD4−CD8− TCRαβ T cells as well as in total Tf and Tf-T1-like CD4−CD8− TCRαβ T cells, which were more pronounced in the HC group than in the SSc group.