IL-1α levels were significantly influenced by T2DM, IL-33 and NLRP3 (p-values 0.02, 0.04, 0.005, 0.004 and 0.004, respectively) while IL-33 was significantly associated with HDL-cholesterol and ILs 1α and NLRP3 (p-values 0.009, 0.004 and 0.007, respectively). Here, IL1A is linked to type 2 diabetes mellitus.