NLRP3 and type 2 diabetes mellitus: The present study assessed the circulating levels of NLRP3 and related ILs (1α, 1β, 33 and 37) in Saudi adults with PD and T2DM and observed that NLRP3 expression was significantly influenced by T2DM status and age, independent of sex, BMI and lipids, and was associated with ILs 18, 1α and 33.