Other miRNAs involved in AD inflammation that might be targets of future immunomodulatory treatments are miR-155, which decreases CTLA-4 levels and increases the proliferation of T helper cells [50,54,56], and miR-146a, a crucial regulator of factors of innate and adaptive immunity which controls immune cell differentiation, antibody production and inflammatory factor secretion [59,60]. Here, CTLA4 is linked to Alzheimer disease.