The development of hyperuricemia has been shown to be accompanied by multiple genetic factors and mutations in the uric acid transporter protein genes SLC2A9 (encoding GLUT9), SLC22A12 (encoding URAT1), SLC17A1 (encoding NPT1) and ABCG2, which were most strongly correlated with changes in serum uric acid levels [1,8,15,21]. The gene discussed is ABCG2; the disease is hyperuricemia.