In the study by Menegazzo et al., serum levels of NETosis biomarkers (cell-free dsDNA, histones, elastase, proteinase-3, neutrophils gelatinase-associated lipocalin (NGAL), and lactoferrin) were measured in 91 patients with pre-diabetes (n = 18), DM2 with bad glucose control (n = 73). Here, PRTN3 is linked to diabetes mellitus.