IGHE and allergic disease: Research on supplementation of live Lactobacillus rhamnosus GG (LGG) has verified its potential as a promising strategy for allergy prevention by decreasing serum IgE levels, lung eosinophil counts, lung Th2 cytokines, AHR, lung matrix metalloproteinase 9 expression, inflammatory cell infiltration, and the concentration of exhaled nitric oxide [9,10,11].