As shown in Figure 4, the increased gene expression of TSLP (3-fold; Figure 4B), IL33 (3-fold; Figure 4C), TARC (2.3-fold; Figure 4D), and MDC (1.78-fold; Figure 4E) in HaCaT keratinocytes treated with AD-inducing agents was significantly downregulated by GMP treatment to values similar to the control conditions, showing the efficacy of GMP reducing atopic inflammatory responses. Here, TSLP is linked to Alzheimer disease.