Overall, the proportion of CD45+ lymphocytes was significantly lower in all the recurrence-free (RFC) lung cancer patients before (Pre RFC, **** p < 0.0001) and three months after surgery (Post RFC, * p < 0.05), and in the cohort of early recurrence (RC) lung cancer patients before surgery (Pre RC; ** p < 0.01), as compared to those of the healthy controls. Here, PTPRC is linked to lung cancer.