Other inducers, such as Aβ1–42 peptide-induced AD mice, also showed increased NF-κB and decreased IκB-α, whereas the administration of polysaccharides SCP from Schisandra Chinensis decreased the nuclear translocation of NF-κB, thereby reducing the expression and release of pro-inflammatory cytokines [79]. The gene discussed is NFKB1; the disease is Alzheimer disease.