SNCA and Parkinson disease: In particular, we focused on three miRNAs known to be involved in the modulation of the SNCA gene—miR-223-3p, miR-7-1-5p, [20,21] and miR-499-3p, the latter targeting a specific sequence of α-Syn 3′UTR containing a PD-associated susceptibility polymorphism (rs17016074) [22].