PLA2G6 and early-onset autosomal dominant Alzheimer disease: Although PLA2 role in the nervous system is not well defined yet, especially due to the great complexity in the expression of PLA2 groups in this system, its implication in membrane remodeling, exocytosis, and neurotransmitter release can explain the involvement in some brain lesions and in neurodegenerative diseases such as Alzheimer’s disease [26].