Moreover, other findings proved that arachidonic acid generated by phosphorylated cPLA2 has a cytotoxic effect and decreases tumor cells’ progression, through reactive oxygen species (ROS) generation and through the increase of cytoplasmic calcium influx [34], in different types of brain cancer including neuroblastoma, glioma, and retinoblastoma [35]. The gene discussed is PLA2G4A; the disease is central nervous system cancer.