In terms of T cells, the abundance of MAIT, TEM%Th, TEMRA%Th, CD45RA+CD27-Th and TEMRA%CD8 in depressed SLE patients was also higher than in non-depressed patients, and no significant differences were observed in the other CD4, CD8, Th and Treg subsets. Here, CD4 is linked to systemic lupus erythematosus.