After 3 days of antibiotics treatment, WBC, ANC, RBC, hemoglobin (Hb), mean cell volume (MCV), serum CRP, and urinary hepcidin–creatinine ratio were all showing reduction in the febrile UTI group (p < 0.001, <0.001, 0.001, <0.001, <0.001, <0.001, and 0.009, respectively). This evidence concerns the gene HAMP and bacterial urinary tract infection.