However, two girls, aged 2.8 years (#29) with positive IAA, and 5 years (#38) with positive anti-IA2/anti-GAD who progressed to overt T1D within a year had mild elevation of anti-TTG-IgA Abs (15.8, and 27.5, <10, respectively), did not start on a gluten-free diet, and achieved reversion of seroconversion by 3 months and 9 months on calcitriol and paricalcitol treatment, and remain negative for 4.3 and 2 years, respectively. This evidence concerns the gene PTPRN and type 1 diabetes mellitus.