IGHE and food allergy: Evidence from a randomized clinical trial of 330 enrolled neonates at risk of atopy suggested that sensitization to CM and food allergies, including CMA and anaphylaxis, risk of asthma, and recurrent wheezing in young children, especially among those with high total IgE levels, was primarily prevented by avoiding CM formula supplementation at least for the first 3 days of life [8,9].