YKL-40 could diagnose neonatal sepsis with a sensitivity of 80% and specificity of 73%, which are almost similar to, or even better than, those reported for Pct, showing a pooled sensitivity of 81% [10] and 85% [11] and specificity of 79% [10] and 54% [11] in meta-analyses. This evidence concerns the gene CHI3L1 and Neonatal sepsis.