The investigation of the altered expression of single lncRNAs in tumors has already identified several molecules such as MALAT1, HOTAIR and H19 as potential useful biomarkers for the diagnosis and prognosis of different types of cancer, including BC, because of their availability from body fluids, even if their mechanisms of action and hence their actual involvement in neoplastic transformation remain unclear [37,38]. Here, MALAT1 is linked to breast cancer.